The Comfort Inn and Suites hotel in Orangeburg, SC is ideally located for both business and leisure travelers with easy access off of Interstate 26. South Carolina State University, Claflin University, Southern Methodist College, Prince of Orange Mall and Hillcrest Golf Course are nearby. Hotel amenities include an indoor pool, exercise room, business center, meeting room, free wired and wireless high-speed Internet in all guest rooms, and free deluxe continental breakfast with hot waffles. This is a smoke-free hotel. Suites and efficiencies with full refrigerators, stoves and dishwashers are offered. Truck parking is available.